Biological function of activation-induced cytidine deaminase (AID)
Activation-induced Cytidine Deaminase (AID) is an essential regulator of B cell diversification, but its full range of action has until recently been an enigma.Based on homology, it was originally proposed to be an RNA-editing enzyme, but so far, no RNA substrates are known.Rather, it functions by deaminating cytidine, and in this manner, coupled w